SalesLoft Cadence currently integrates with Salesforce. If you do not have Salesforce, you do not lose any SalesLoft Cadence application functionality (saving and sharing templates, email intelligence, in-app dialer, etc.).
If you are using another CRM, you can log your emails sent from SalesLoft Cadence by setting up a BCC address. We do plan to build out integration with more CRMs as the application matures, and you can always add your feature requests to our idea exchange to expedite that process!